Growth Inhibition of Tobacco Tissue Cultures with 6-Azauracil, 6-Azauridine and Maleic Hydrazide

Studies on the Carcinostatic Activity in Mice of 6-Azauracil Riboside (Azauridine), In Comparison with that of 6-Azauracil ‡

The Fate of Maleic Hydrazide on Tobacco during Smoking

Tobacco mainstream smoke (MSS) and sidestream smoke (SSS), butts, and ashes from commercial cigarettes and maleic hydrazide (MH) spiked cigarettes were analyzed for their MH contents. The MH transfer rates obtained for MSS ranged from 1.4% to 3.7%, for SSS ranged from 0.2% to 0.9%, and for butts ranged from 1.1% to 1.9%. And as expected, MH is absent in ashes. The transfer rate of MH into mains...

Photoelectron spectroscopy of the 6-azauracil anion.

We report the photoelectron spectrum of the 6-azauracil anion. The spectrum is dominated by a broad band exhibiting a maximum at an electron binding energy (EBE) of 1.2 eV. This spectral pattern is indicative of a valence anion. Our calculations were carried out using ab initio electron propagator and other many-body methods. Comparison of the anion and corresponding neutral of 6-azauracil with...

Specific activities of uridine phosphorylase and uridine kinase in Ehrlich ascites carcinoma cells and 6-azauracil- and 6-azauridine-treated sublines in successive transplant generations.

THE development of resistance to 5-fluorouracil (FU) in Ehrlich ascites carcin-oma (EAC) cells has been accompanied by decreases in the activities of uridine kinase (Reichard et al., 1962) or of uridine phosphorylase and deoxyuridine phos-phorylase (Reichard, Skold and Klein, 1959). These enzymes of the " uracil pathway " of pyrimidine biosynthesis are involved in the conversion of FU to its ac...

Effect of Triiodobenzoic Acid and Maleic Hydrazide

ham University (Newcastle Division, King's College) 1957. 25. KORNBERG, H. and KREBS, H. A. Synthesis of cell constituents from C-units by a modified tricarboxylic acid cycle. Nature 179: 988-991. 1957. 26. BRADBEER, J. W. Some carbohydrate and acid conversions in Kalanchoe crenata. Ph.D. Thesis, Durham University (Newcastle Di-ision, King's College) 1954. 27. STILLER, M. Experiments on the rel...